Version 5.4
Homo sapiens Protein: BTD
Summary
InnateDB Protein IDBP-366445.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BTD
Protein Name biotinidase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000388212
InnateDB Gene IDBG-21076 (BTD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004075 biotin carboxylase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0047708 biotinidase activity
Biological Process
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0006768 biotin metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0007417 central nervous system development
GO:0008544 epidermis development
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005759 mitochondrial matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003010 Carbon-nitrogen hydrolase
IPR012101 Biotinidase, eukaryotic
PFAM PF00795
PRINTS
PIRSF PIRSF011861
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43251
PhosphoSite PhosphoSite-P43251
TrEMBL F8W1Q3
UniProt Splice Variant
Entrez Gene 686
UniGene Hs.517830
RefSeq NP_001268652
HUGO HGNC:1122
OMIM 609019
CCDS CCDS63563
HPRD 08359
IMGT
EMBL AC027129 AF018630 AF018631 AK294301 AK297033 AK313252 BC012099 CH471055 U03274
GenPept AAC04318 AAC21679 AAH12099 BAG36062 BAG57582 BAG59561 EAW64254

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca