Version 5.4
Homo sapiens Protein: MX1
Summary
InnateDB Protein IDBP-367165.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MX1
Protein Name myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
Synonyms IFI-78K; IFI78; MX; MxA;
Species Homo sapiens
Ensembl Protein ENSP00000400923
InnateDB Gene IDBG-3941 (MX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001401 Dynamin, GTPase domain
IPR022812 Dynamin superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00350
PRINTS PR00195
PIRSF
SMART SM00053
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H9KVD3
UniProt Splice Variant
Entrez Gene 4599
UniGene Hs.679475
RefSeq
HUGO HGNC:7532
OMIM 147150
CCDS
HPRD 00919
IMGT
EMBL AL773577 AL773578 AP001610
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca