Version 5.4
Homo sapiens Protein: DERA
Summary
InnateDB Protein IDBP-368472.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DERA
Protein Name deoxyribose-phosphate aldolase (putative)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000416583
InnateDB Gene IDBG-21696 (DERA)
Protein Structure
UniProt Annotation
Function Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004139 deoxyribose-phosphate aldolase activity
GO:0016829 lyase activity
Biological Process
GO:0009264 deoxyribonucleotide catabolic process
GO:0046121 deoxyribonucleoside catabolic process
GO:0046386 deoxyribose phosphate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002915 DeoC/FbaB/ lacD aldolase
IPR011343 Deoxyribose-phosphate aldolase
PFAM PF01791
PRINTS
PIRSF PIRSF038992
PIRSF001357
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y315
PhosphoSite PhosphoSite-Q9Y315
TrEMBL G3V158
UniProt Splice Variant
Entrez Gene 51071
UniGene Hs.39429
RefSeq NP_057038
HUGO HGNC:24269
OMIM
CCDS CCDS44838
HPRD 13138
IMGT
EMBL AC022073 AF132960 AK222541 BC056234 CH471094
GenPept AAD27735 AAH56234 BAD96261 EAW96357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca