Version 5.4
| Homo sapiens Protein: HOXA4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-369238.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | HOXA4 | ||||||||
| Protein Name | homeobox A4 | ||||||||
| Synonyms | HOX1; HOX1D; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000408845 | ||||||||
| InnateDB Gene | IDBG-10384 (HOXA4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT- 3'. | ||||||||
| Subcellular Localization | Nucleus. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Embryonic nervous system. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001356
Homeobox domain IPR009057 Homeodomain-like IPR017995 Homeobox protein, antennapedia type IPR020479 Homeodomain, metazoa |
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| PFAM |
PF00046
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| PRINTS |
PR00025
PR00024 |
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| PIRSF | |||||||||
| SMART |
SM00389
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q00056 | ||||||||
| PhosphoSite | PhosphoSite-Q00056 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 3201 | ||||||||
| UniGene | Hs.533357 | ||||||||
| RefSeq | |||||||||
| HUGO | HGNC:5105 | ||||||||
| OMIM | 142953 | ||||||||
| CCDS | CCDS5405 | ||||||||
| HPRD | 00841 | ||||||||
| IMGT | |||||||||
| EMBL | AC004080 CH236948 CH471073 M28199 M74297 | ||||||||
| GenPept | AAA53290 AAA58664 EAL24224 EAW93872 | ||||||||