Version 5.4
Homo sapiens Protein: GCKR
Summary
InnateDB Protein IDBP-370006.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GCKR
Protein Name glucokinase (hexokinase 4) regulator
Synonyms FGQTL5; GKRP;
Species Homo sapiens
Ensembl Protein ENSP00000398303
InnateDB Gene IDBG-39958 (GCKR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070095 fructose-6-phosphate binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0005975 carbohydrate metabolic process
GO:0008645 hexose transport
GO:0009750 response to fructose
GO:0010827 regulation of glucose transport
GO:0015758 glucose transport
GO:0033132 negative regulation of glucokinase activity
GO:0044281 small molecule metabolic process
GO:0046415 urate metabolic process
GO:0055085 transmembrane transport
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14397
PhosphoSite PhosphoSite-Q14397
TrEMBL
UniProt Splice Variant
Entrez Gene 2646
UniGene Hs.89771
RefSeq
HUGO HGNC:4196
OMIM 600842
CCDS
HPRD 02909
IMGT
EMBL AC074117 AK298448 AY320034 BC130481 BC130483 Y09592 Y09593 Z48475
GenPept AAI30482 AAI30484 AAP72013 AAY14850 BAG60664 CAA70779 CAA88367 CAB61828

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca