InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLEKHA8

Summary

InnateDB Protein

IDBP-370460.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLEKHA8

Protein Name

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000407802

InnateDB Gene

IDBG-10971 (PLEKHA8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0017089	glycolipid transporter activity
GO:0051861	glycolipid binding
GO:0070273	phosphatidylinositol-4-phosphate binding
GO:0097001	ceramide binding

Biological Process

GO:0006869	lipid transport
GO:0015031	protein transport
GO:0035621	ER to Golgi ceramide transport
GO:0046836	glycolipid transport

Cellular Component

GO:0005737	cytoplasm
GO:0005802	trans-Golgi network
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001849 Pleckstrin homology domain
IPR014830 Glycolipid transfer protein domain

PFAM

PF00169
PF08718

PRINTS

PIRSF

SMART

SM00233

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

J3KQS5

UniProt Splice Variant

Entrez Gene

84725

UniGene

Hs.734170

RefSeq

XP_005249955

HUGO

HGNC:30037

OMIM

608639

CCDS

HPRD

10555

IMGT

EMBL

AC007036 AC007285 AF308300 AF380162 AK023180 AK294857 BC002838 BC053990 CH471073

GenPept

AAG48267 AAH02838 AAH53990 AAK55424 BAB14449 BAG57961 EAW93930