Version 5.4
Homo sapiens Protein: POC5
Summary
InnateDB Protein IDBP-371933.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POC5
Protein Name POC5 centriolar protein homolog (Chlamydomonas)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000410216
InnateDB Gene IDBG-29402 (POC5)
Protein Structure
UniProt Annotation
Function Essential for the assembly of the distal half of centrioles, required for centriole elongation. {ECO:0000269PubMed:19349582}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:19349582}. Note=Localized to the distal portion of centrioles.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NA72
PhosphoSite PhosphoSite-Q8NA72
TrEMBL D6RJ06
UniProt Splice Variant
Entrez Gene 134359
UniGene Hs.432726
RefSeq NP_001092741
HUGO HGNC:26658
OMIM
CCDS CCDS47236
HPRD 08188
IMGT
EMBL AC010245 AC025170 AK093098 AK296071 BC065750 BC101325 BC101326 BC101327 BC101328
GenPept AAH65750 AAI01326 AAI01327 AAI01328 BAC04054 BAG58829

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca