Version 5.4
Homo sapiens Protein: ANXA1
Summary
InnateDB Protein IDBP-372950.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANXA1
Protein Name annexin A1
Synonyms ANX1; LPC1;
Species Homo sapiens
Ensembl Protein ENSP00000412489
InnateDB Gene IDBG-71054 (ANXA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 88 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 88 [view]
Protein-Protein 87 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004859 phospholipase inhibitor activity
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0043086 negative regulation of catalytic activity
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR001464 Annexin
IPR002388 Annexin, type I
IPR018502 Annexin repeat
PFAM PF00191
PRINTS PR00196
PR00197
PIRSF
SMART SM00335
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T3N1
UniProt Splice Variant
Entrez Gene 301
UniGene Hs.595342
RefSeq
HUGO HGNC:533
OMIM 151690
CCDS
HPRD 01060
IMGT
EMBL AL359997
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca