Version 5.4
Homo sapiens Protein: CA1
Summary
InnateDB Protein IDBP-373032.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA1
Protein Name carbonic anhydrase I
Synonyms CA-I; CAB; Car1; HEL-S-11;
Species Homo sapiens
Ensembl Protein ENSP00000392338
InnateDB Gene IDBG-27139 (CA1)
Protein Structure
UniProt Annotation
Function Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. {ECO:0000269PubMed:10550681}.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015701 bicarbonate transport
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001148 Alpha carbonic anhydrase
PFAM PF00194
PRINTS
PIRSF
SMART SM01057
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P00915
PhosphoSite PhosphoSite-P00915
TrEMBL V9HWE3
UniProt Splice Variant
Entrez Gene 759
UniGene Hs.23118
RefSeq NP_001278897
HUGO HGNC:1368
OMIM 114800
CCDS CCDS6237
HPRD 00265
IMGT
EMBL AC025800 BC027890 CH471068 EU794595 M33987 X05014
GenPept AAA51910 AAH27890 ACJ13649 CAA28663 EAW87129 EAW87130 EAW87131 EAW87132

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca