Version 5.4
Homo sapiens Protein: MZT1
Summary
InnateDB Protein IDBP-37331.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MZT1
Protein Name mitotic spindle organizing protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367049
InnateDB Gene IDBG-37329 (MZT1)
Protein Structure
UniProt Annotation
Function Required for gamma-tubulin complex recruitment to the centrosome. {ECO:0000269PubMed:20360068}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:20360068}. Cytoplasm, cytoskeleton, spindle {ECO:0000269PubMed:20360068}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0033566 gamma-tubulin complex localization
Cellular Component
GO:0005813 centrosome
GO:0005819 spindle
GO:0008274 gamma-tubulin ring complex
Protein Structure and Domains
PDB ID
InterPro IPR022214 Protein of unknown function DUF3743
PFAM PF12554
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08AG7
PhosphoSite PhosphoSite-Q08AG7
TrEMBL
UniProt Splice Variant
Entrez Gene 440145
UniGene Hs.28465
RefSeq NP_001065243
HUGO HGNC:33830
OMIM 613448
CCDS CCDS31990
HPRD
IMGT
EMBL AL138695 AL356754 BC125183
GenPept AAI25184 CAH70226 CAH72711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca