Version 5.4
Homo sapiens Protein: CERS5
Summary
InnateDB Protein IDBP-374805.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERS5
Protein Name ceramide synthase 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000389050
InnateDB Gene IDBG-32436 (CERS5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006665 sphingolipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR006634 TRAM/LAG1/CLN8 homology domain
IPR009057 Homeodomain-like
IPR016439 Longevity assurance, LAG1/LAC1
PFAM PF00046
PF03798
PRINTS
PIRSF PIRSF005225
SMART SM00389
SM00724
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N5B7
PhosphoSite PhosphoSite-Q8N5B7
TrEMBL
UniProt Splice Variant
Entrez Gene 91012
UniGene Hs.694201
RefSeq NP_001268660
HUGO HGNC:23749
OMIM 615335
CCDS CCDS61120
HPRD 13963
IMGT
EMBL AC074032 AC139016 AK300937 BC032565 CH471111
GenPept AAH32565 BAG62566 EAW58133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca