Version 5.4
Homo sapiens Protein: NUDCD1
Summary
InnateDB Protein IDBP-375025.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDCD1
Protein Name NudC domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000410707
InnateDB Gene IDBG-32541 (NUDCD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Isoform 1: Cytoplasm. Nucleus.Isoform 2: Cytoplasm.Isoform 3: Cytoplasm. Nucleus.
Disease Associations
Tissue Specificity Isoform 1 is specifically expressed in leukemias and a variety of solid tumor cell lines and is also detected in testis and heart. Isoform 2 is predominantly expressed in testis and weakly expressed in tumor cells. {ECO:0000269PubMed:11416219, ECO:0000269PubMed:14688378}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002376 immune system process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR007052 CS domain
IPR008978 HSP20-like chaperone
PFAM PF04969
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96RS6
PhosphoSite PhosphoSite-Q96RS6
TrEMBL
UniProt Splice Variant
Entrez Gene 84955
UniGene Hs.594025
RefSeq NP_001121683
HUGO HGNC:24306
OMIM 606109
CCDS CCDS47910
HPRD 16200
IMGT
EMBL AC021237 AF283301 AF283302 AF521133 AK027897 AK301278 AL832317 BC000967 BC031258 BC043406
GenPept AAH00967 AAH31258 AAH43406 AAK73017 AAM69373 AAQ08823 BAB55439 BAG62838 CAD38612

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca