Version 5.4
Homo sapiens Protein: ST7
Summary
InnateDB Protein IDBP-37515.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST7
Protein Name suppression of tumorigenicity 7
Synonyms ETS7q; FAM4A; FAM4A1; HELG; RAY1; SEN4; TSG7;
Species Homo sapiens
Ensembl Protein ENSP00000265437
InnateDB Gene IDBG-37511 (ST7)
Protein Structure
UniProt Annotation
Function May act as a tumor suppressor. {ECO:0000269PubMed:16474848}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitously expressed, with highest levels in heart, liver and pancreas. {ECO:0000269PubMed:10889047, ECO:0000269PubMed:11279520}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 11 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007311 ST7
PFAM PF04184
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRC1
PhosphoSite PhosphoSite-Q9NRC1
TrEMBL X5DRA0
UniProt Splice Variant
Entrez Gene 93655
UniGene Hs.368131
RefSeq NP_068708
HUGO HGNC:11351
OMIM 600833
CCDS CCDS5770
HPRD 09015
IMGT
EMBL AC002542 AC003987 AC106873 AF234882 AF234883 AF234886 AF415174 AJ277291 AK093212 AY009152 AY009153 BC030954 BC075855 CH236947 CH471070 CR936656 KJ534947
GenPept AAF85945 AAF85946 AAF85949 AAG37720 AAG37721 AAH30954 AAH75855 AAL85662 AAS07414 AAS07415 AAS07529 AHW56587 BAC04097 CAB86869 CAI56794 EAL24356 EAL24357 EAW83520

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca