InnateDB Protein
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IDBP-37558.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TLCD1
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Protein Name
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TLC domain containing 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000292090
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InnateDB Gene
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IDBG-37556 (TLCD1)
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Protein Structure
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Function |
Calcium channel facilitator that increases calcium flux by generating a larger window current and slowing inactivation of the L-type CACNA1C/CaV1.2 channel. Regulation of intracellular calcium by Calfacilitin is required for neural plate formation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR006634
TRAM/LAG1/CLN8 homology domain
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PFAM |
PF03798
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PRINTS |
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PIRSF |
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SMART |
SM00724
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TIGRFAMs |
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Modification |
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SwissProt |
Q96CP7
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PhosphoSite |
PhosphoSite-Q96CP7
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TrEMBL |
K7ELX5
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UniProt Splice Variant |
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Entrez Gene |
116238
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UniGene |
Hs.713008
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RefSeq |
NP_612472
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HUGO |
HGNC:25177
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OMIM |
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CCDS |
CCDS11242
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HPRD |
14015
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IMGT |
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EMBL |
AC010761
BC014072
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GenPept |
AAH14072
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