Version 5.4
Homo sapiens Protein: MLN
Summary
InnateDB Protein IDBP-375974.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLN
Protein Name motilin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000388825
InnateDB Gene IDBG-83276 (MLN)
Protein Structure
UniProt Annotation
Function Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005179 hormone activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007267 cell-cell signaling
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR006737 Motilin/ghrelin-associated peptide
IPR006738 Motilin/ghrelin
PFAM PF04643
PF04644
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P12872
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4295
UniGene Hs.2813
RefSeq NP_002409
HUGO HGNC:7141
OMIM 158270
CCDS CCDS4786
HPRD 15931
IMGT
EMBL AL138889 AL158049 BC069675 BC112314 BC143981 CH471081 M30278 M30279 M30280 M30281 X15393 X15394 X15395 X15396 Y00695
GenPept AAA59860 AAH69675 AAI12315 AAI43982 CAA33448 CAA68690 CAI21441 CAI21526 EAX03752 EAX03753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca