Version 5.4
Homo sapiens Protein: FGF16
Summary
InnateDB Protein IDBP-376209.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGF16
Protein Name fibroblast growth factor 16
Synonyms FGF-16; MF4;
Species Homo sapiens
Ensembl Protein ENSP00000399324
InnateDB Gene IDBG-77506 (FGF16)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005104 fibroblast growth factor receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008152 metabolic process
GO:0008286 insulin receptor signaling pathway
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009266 response to temperature stimulus
GO:0009887 organ morphogenesis
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0070349 positive regulation of brown fat cell proliferation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR002209 Fibroblast growth factor family
IPR008996 Cytokine, IL-1-like
IPR028142 IL-1 family/FGF family
PFAM
PRINTS PR00263
PR00262
PIRSF
SMART SM00442
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43320
PhosphoSite PhosphoSite-O43320
TrEMBL
UniProt Splice Variant
Entrez Gene 8823
UniGene Hs.537037
RefSeq NP_003859
HUGO HGNC:3672
OMIM 300827
CCDS CCDS75996
HPRD 04764
IMGT
EMBL AB009391
GenPept BAA24956

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca