Version 5.4
Homo sapiens Protein: IL5
Summary
InnateDB Protein IDBP-376310.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL5
Protein Name interleukin 5 (colony-stimulating factor, eosinophil)
Synonyms EDF; IL-5; TRF;
Species Homo sapiens
Ensembl Protein ENSP00000409825
InnateDB Gene IDBG-42236 (IL5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 10 [view]
Protein-DNA 11 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005137 interleukin-5 receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0006955 immune response
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000186 Interleukin-5
IPR009079 Four-helical cytokine-like, core
PFAM PF02025
PRINTS PR00432
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JQP9
UniProt Splice Variant
Entrez Gene 3567
UniGene Hs.2247
RefSeq
HUGO HGNC:6016
OMIM 147850
CCDS
HPRD 00997
IMGT
EMBL AC116366
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca