Version 5.4
Homo sapiens Protein: LY6H
Summary
InnateDB Protein IDBP-377259.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LY6H
Protein Name lymphocyte antigen 6 complex, locus H
Synonyms NMLY6;
Species Homo sapiens
Ensembl Protein ENSP00000409899
InnateDB Gene IDBG-38152 (LY6H)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007399 nervous system development
GO:0009887 organ morphogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001526 CD59 antigen
IPR016054 Ly-6 antigen / uPA receptor -like
PFAM PF00021
PRINTS
PIRSF
SMART SM00134
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94772
PhosphoSite PhosphoSite-O94772
TrEMBL
UniProt Splice Variant
Entrez Gene 4062
UniGene Hs.641724
RefSeq NP_002338
HUGO HGNC:6728
OMIM 603625
CCDS CCDS6396
HPRD 04691
IMGT
EMBL AB012293 AC083982 AK314139 BC028894 BC030192 BX419752 CH471162 CR457034
GenPept AAH28894 AAH30192 BAA34115 BAG36829 CAG33315 EAW82277

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca