InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TSTA3

Summary

InnateDB Protein

IDBP-377535.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TSTA3

Protein Name

tissue specific transplantation antigen P35B

Synonyms

FX; P35B; SDR4E1;

Species

Homo sapiens

Ensembl Protein

ENSP00000398803

InnateDB Gene

IDBG-38856 (TSTA3)

Protein Structure

UniProt Annotation

Function

Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. {ECO:0000269PubMed:8910301}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0009055	electron carrier activity
GO:0016853	isomerase activity
GO:0042356	GDP-4-dehydro-D-rhamnose reductase activity
GO:0050577	GDP-L-fucose synthase activity
GO:0050662	coenzyme binding

Biological Process

GO:0007159	leukocyte cell-cell adhesion
GO:0019673	GDP-mannose metabolic process
GO:0019835	cytolysis
GO:0042351	'de novo' GDP-L-fucose biosynthetic process
GO:0044237	cellular metabolic process
GO:0055114	oxidation-reduction process