InnateDB Protein
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IDBP-378101.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FKBP15
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Protein Name
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FK506 binding protein 15, 133kDa
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Synonyms
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FKBP133; KIAA0674; PPP1R76;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000415733
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InnateDB Gene
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IDBG-81519 (FKBP15)
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Protein Structure
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Function |
May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule- based movement. {ECO:0000250, ECO:0000269PubMed:19121306}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}. Early endosome {ECO:0000269PubMed:19121306}. Note=Present in axons and neuronal growth cones. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003755
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peptidyl-prolyl cis-trans isomerase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001179
Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
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PFAM |
PF00254
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-Q5T1M5
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TrEMBL |
X6RKW4
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UniProt Splice Variant |
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Entrez Gene |
23307
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UniGene |
Hs.703312
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RefSeq |
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HUGO |
HGNC:23397
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL449105
AL449305
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GenPept |
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