InnateDB Protein
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IDBP-378888.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMED3
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Protein Name
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transmembrane emp24 protein transport domain containing 3
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Synonyms
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C15orf22; P24B; p26;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000414983
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InnateDB Gene
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IDBG-25466 (TMED3)
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Protein Structure
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Function |
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. {ECO:0000269PubMed:10852829}.
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Subcellular Localization |
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Probably cycles between compartments of the early secretatory pathway.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009038
GOLD
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PFAM |
PF01105
PF13897
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Y3Q3
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PhosphoSite |
PhosphoSite-Q9Y3Q3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23423
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UniGene |
Hs.714066
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RefSeq |
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HUGO |
HGNC:28889
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OMIM |
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CCDS |
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HPRD |
18200
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IMGT |
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EMBL |
AC011797
AC027811
AJ132270
AK289434
AK297710
AL109672
AY358974
BC000027
BC010853
BC017495
BC022232
BC111547
CR457384
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GenPept |
AAH00027
AAH10853
AAH17495
AAH22232
AAI11548
AAQ89333
BAF82123
BAG60067
CAB40416
CAB52017
CAG33665
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