Version 5.4
Homo sapiens Protein: GML
Summary
InnateDB Protein IDBP-37890.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GML
Protein Name glycosylphosphatidylinositol anchored molecule like protein
Synonyms LY6DL;
Species Homo sapiens
Ensembl Protein ENSP00000220940
InnateDB Gene IDBG-37888 (GML)
Protein Structure
UniProt Annotation
Function May play a role in the apoptotic pathway or cell-cycle regulation induced by p53/TP53 after DNA damage.
Subcellular Localization Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008285 negative regulation of cell proliferation
Cellular Component
GO:0005886 plasma membrane
GO:0019898 extrinsic component of membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR016054 Ly-6 antigen / uPA receptor -like
PFAM
PRINTS
PIRSF
SMART SM00134
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99445
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 2765
UniGene Hs.661218
RefSeq NP_002057
HUGO HGNC:4375
OMIM 602370
CCDS CCDS6391
HPRD 03844
IMGT
EMBL AB000381 BC074930 BC126336 BC126338 D84290
GenPept AAH74930 AAI26337 AAI26339 BAA12300 BAA19961

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca