Version 5.4
Homo sapiens Protein: IFI35
Summary
InnateDB Protein IDBP-379238.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFI35
Protein Name interferon-induced protein 35
Synonyms IFP35;
Species Homo sapiens
Ensembl Protein ENSP00000395590
InnateDB Gene IDBG-52075 (IFI35)
Protein Structure
UniProt Annotation
Function Not yet known.
Subcellular Localization Nucleus. Note=Nuclear following IFN treatment.
Disease Associations
Tissue Specificity In a wide range of cell types, including fibroblasts, macrophages, and epithelial cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR009909 Nmi/IFP 35 domain
IPR009938 Nmi/IFP 35 domain, N-terminal
PFAM PF07292
PF07334
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P80217
PhosphoSite PhosphoSite-P80217
TrEMBL
UniProt Splice Variant
Entrez Gene 3430
UniGene Hs.604861
RefSeq NP_005524
HUGO HGNC:5399
OMIM 600735
CCDS CCDS11450
HPRD 02844
IMGT
EMBL AC055866 BC001356 L78833 U72882
GenPept AAB61703 AAC37597 AAH01356

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca