InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GNS

Summary

InnateDB Protein

IDBP-379478.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNS

Protein Name

glucosamine (N-acetyl)-6-sulfatase

Synonyms

G6S;

Species

Homo sapiens

Ensembl Protein

ENSP00000413130

InnateDB Gene

IDBG-45087 (GNS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.

Experimentally validated
Total	23 [view]
Protein-Protein	20 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008449	N-acetylglucosamine-6-sulfatase activity
GO:0008484	sulfuric ester hydrolase activity

Biological Process

GO:0008152	metabolic process
GO:0030203	glycosaminoglycan metabolic process

Cellular Component

GO:0005764

lysosome

Protein Structure and Domains

PDB ID

InterPro

IPR000917 Sulfatase
IPR012251 N-acetylglucosamine-6-sulfatase
IPR017850 Alkaline-phosphatase-like, core domain

PFAM

PF00884

PRINTS

PIRSF

PIRSF036666

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H7C3P4

UniProt Splice Variant

Entrez Gene

2799

UniGene

Hs.682295

RefSeq

HUGO

HGNC:4422

OMIM

607664

CCDS

HPRD

09637

IMGT

EMBL

AC025262 CH471054

GenPept

EAW97139