Version 5.4
Homo sapiens Protein: GLG1
Summary
InnateDB Protein IDBP-380758.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLG1
Protein Name golgi glycoprotein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000406946
InnateDB Gene IDBG-42039 (GLG1)
Protein Structure
UniProt Annotation
Function Binds fibroblast growth factor and E-selectin (cell- adhesion lectin on endothelial cells mediating the binding of neutrophils).
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:2355176}; Single-pass type I membrane protein {ECO:0000269PubMed:2355176}.
Disease Associations
Tissue Specificity Widely expressed. Highest levels in pancreas, skeletal muscle, placenta, heart, testis and ovary. Also found in the kidney, liver, lung and brain. {ECO:0000269PubMed:9182700}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0050900 leukocyte migration
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001893 Cysteine-rich Golgi apparatus protein 1 repeat
PFAM PF00839
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92896
PhosphoSite PhosphoSite-Q92896
TrEMBL Q6ZMF1
UniProt Splice Variant
Entrez Gene 2734
UniGene Hs.109731
RefSeq NP_001139138
HUGO HGNC:4316
OMIM 600753
CCDS CCDS45526
HPRD 02855
IMGT
EMBL AC009053 AC009153 AC109599 AK172806 AK304156 BC060822 CH471114 U28811 U64791
GenPept AAB02178 AAB06460 AAH60822 BAD18777 BAH14120 EAW95682 EAW95683 EAW95686

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca