Homo sapiens Protein: LRRC25
Summary
InnateDB Protein IDBP-38111.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC25
Protein Name leucine rich repeat containing 25
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000340983
InnateDB Gene IDBG-38109 (LRRC25)
Protein Structure
UniProt Annotation
Function May be involved in the activation of cells of innate and acquired immunity. {ECO:0000269PubMed:12384430}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. {ECO:0000269PubMed:12384430}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N386
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 126364
UniGene Hs.332156
RefSeq NP_660299
HUGO HGNC:29806
OMIM 607518
CCDS CCDS12377
HPRD 09597
IMGT
EMBL AJ422148 AK095435 AY358151 BC071640 BC093842
GenPept AAH71640 AAH93842 AAQ88518 BAC04548 CAD19531