InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UBA3

Summary

InnateDB Protein

IDBP-381129.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UBA3

Protein Name

ubiquitin-like modifier activating enzyme 3

Synonyms

hUBA3; NAE2; UBE1C;

Species

Homo sapiens

Ensembl Protein

ENSP00000400294

InnateDB Gene

IDBG-43924 (UBA3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	38 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005524	ATP binding
GO:0008641	small protein activating enzyme activity
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0006464	cellular protein modification process
GO:0045116	protein neddylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000127 Ubiquitin-activating enzyme repeat
IPR000594 UBA/THIF-type NAD/FAD binding fold
IPR009036 Molybdenum cofactor biosynthesis, MoeB
IPR014929 E2 binding
IPR019572 Ubiquitin-activating enzyme

PFAM

PF02134
PF00899
PF08825
PF10585

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-