InnateDB Protein
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IDBP-381263.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SMAP2
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Protein Name
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small ArfGAP2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000389895
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InnateDB Gene
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IDBG-96929 (SMAP2)
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Protein Structure
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Function |
GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm. Note=Detected in multiple foci throughout the cytoplasm and in juxtanuclear structures. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001164
Arf GTPase activating protein
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PFAM |
PF01412
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PRINTS |
PR00405
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PIRSF |
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SMART |
SM00105
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-Q8WU79
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TrEMBL |
X6RCC3
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UniProt Splice Variant |
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Entrez Gene |
64744
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UniGene |
Hs.15200
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RefSeq |
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HUGO |
HGNC:25082
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OMIM |
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CCDS |
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HPRD |
12442
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IMGT |
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EMBL |
AL031985
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GenPept |
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