InnateDB Protein
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IDBP-381438.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NEDD1
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Protein Name
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neural precursor cell expressed, developmentally down-regulated 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000411307
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InnateDB Gene
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IDBG-52158 (NEDD1)
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Protein Structure
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Function |
Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. {ECO:0000269PubMed:19029337, ECO:0000269PubMed:19509060}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:19029337}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
69
[view]
|
Protein-Protein |
66
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
2
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001680
WD40 repeat
IPR017986
WD40-repeat-containing domain
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PFAM |
PF00400
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PRINTS |
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PIRSF |
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SMART |
SM00320
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NHV4
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PhosphoSite |
PhosphoSite-Q8NHV4
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TrEMBL |
G3V4I9
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UniProt Splice Variant |
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Entrez Gene |
121441
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UniGene |
Hs.743848
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RefSeq |
NP_001128649
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HUGO |
HGNC:7723
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OMIM |
600372
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CCDS |
CCDS44956
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HPRD |
02655
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IMGT |
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EMBL |
AC007564
AC013417
AK093221
AK303656
AK315821
BC027605
CH471054
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GenPept |
AAH27605
BAC04099
BAF98712
BAG64657
EAW97577
EAW97579
EAW97580
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