Version 5.4
Homo sapiens Protein: ELF2
Summary
InnateDB Protein IDBP-38214.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELF2
Protein Name E74-like factor 2 (ets domain transcription factor)
Synonyms EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2;
Species Homo sapiens
Ensembl Protein ENSP00000368867
InnateDB Gene IDBG-38206 (ELF2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030154 cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000418 Ets domain
IPR022084 Transcription factor Elf, N-terminal
PFAM PF00178
PF12310
PRINTS PR00454
PIRSF
SMART SM00413
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15723
PhosphoSite PhosphoSite-Q15723
TrEMBL D6R9B1
UniProt Splice Variant
Entrez Gene 1998
UniGene Hs.656593
RefSeq NP_001263388
HUGO HGNC:3317
OMIM
CCDS CCDS64063
HPRD 16856
IMGT
EMBL AC024032 AC093602 AF256222 AF256223 BC034951 BC065025 U43188 U43189
GenPept AAB37759 AAB37760 AAB37761 AAF67195 AAF67196 AAH34951 AAH65025

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca