Version 5.4
Homo sapiens Protein: SLC6A8
Summary
InnateDB Protein IDBP-382933.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A8
Protein Name solute carrier family 6 (neurotransmitter transporter, creatine), member 8
Synonyms CCDS1; CRT; CRTR; CT1; CTR5;
Species Homo sapiens
Ensembl Protein ENSP00000403041
InnateDB Gene IDBG-89549 (SLC6A8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005308 creatine transmembrane transporter activity
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006600 creatine metabolic process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0006836 neurotransmitter transport
GO:0006936 muscle contraction
GO:0008150 biological_process
GO:0015881 creatine transport
GO:0034641 cellular nitrogen compound metabolic process
GO:0044281 small molecule metabolic process
GO:1902598 creatine transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000175 Sodium:neurotransmitter symporter
IPR002984 Sodium:neurotransmitter symporter, creatine
PFAM PF00209
PRINTS PR00176
PR01199
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48029
PhosphoSite PhosphoSite-P48029
TrEMBL
UniProt Splice Variant
Entrez Gene 6535
UniGene Hs.540696
RefSeq NP_001136278
HUGO HGNC:11055
OMIM 300036
CCDS CCDS48190
HPRD 02073
IMGT
EMBL AK295495 BC012355 BC081558 EU280316 L31409 S74039 U17986 U36341 U52111 Z66539
GenPept AAA79507 AAA86990 AAB32284 AAC41688 AAH12355 AAH81558 ABZ82022 BAG58415 CAA91442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca