InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KANSL3

Summary

InnateDB Protein

IDBP-383026.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KANSL3

Protein Name

KIAA1310

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000396749

InnateDB Gene

IDBG-61798 (KANSL3)

Protein Structure

UniProt Annotation

Function

As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000269PubMed:20018852}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:20018852}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0043995	histone acetyltransferase activity (H4-K5 specific)
GO:0043996	histone acetyltransferase activity (H4-K8 specific)
GO:0046972	histone acetyltransferase activity (H4-K16 specific)

Biological Process

GO:0006325	chromatin organization
GO:0043981	histone H4-K5 acetylation
GO:0043982	histone H4-K8 acetylation
GO:0043984	histone H4-K16 acetylation

Cellular Component

GO:0000123	histone acetyltransferase complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0043231	intracellular membrane-bounded organelle