Version 5.4
Homo sapiens Protein: PPP2R1B
Summary
InnateDB Protein IDBP-383036.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP2R1B
Protein Name protein phosphatase 2, regulatory subunit A, beta
Synonyms PP2A-Abeta; PR65B;
Species Homo sapiens
Ensembl Protein ENSP00000410671
InnateDB Gene IDBG-70936 (PPP2R1B)
Protein Structure
UniProt Annotation
Function The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 102 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 102 [view]
Protein-Protein 100 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0060561 apoptotic process involved in morphogenesis
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID
InterPro IPR000357 HEAT
IPR016024 Armadillo-type fold
IPR021133 HEAT, type 2
PFAM PF02985
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30154
PhosphoSite PhosphoSite-P30154
TrEMBL
UniProt Splice Variant
Entrez Gene 5519
UniGene Hs.629987
RefSeq NP_859051
HUGO HGNC:9303
OMIM 603113
CCDS CCDS53706
HPRD 04384
IMGT
EMBL AF083425 AF083426 AF083427 AF083428 AF083429 AF083430 AF083431 AF083432 AF083433 AF083434 AF083435 AF083436 AF083437 AF083438 AF083439 AF087438 AF163473 AK294716 AK296455 AK301705 AP000925 AP001781 BC027596 CH471065 EF445011 M65254
GenPept AAA59983 AAC63525 AAC69624 AAG39644 AAH27596 ACA06046 ACA06047 BAG57867 BAG59103 BAG63177 EAW67150 EAW67151

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca