Version 5.4
Homo sapiens Protein: MUCL1
Summary
InnateDB Protein IDBP-38306.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MUCL1
Protein Name mucin-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000311364
InnateDB Gene IDBG-38304 (MUCL1)
Protein Structure
UniProt Annotation
Function May play a role as marker for the diagnosis of metastatic breast cancer. {ECO:0000269PubMed:12019145, ECO:0000269PubMed:12595743, ECO:0000269PubMed:15684711}.
Subcellular Localization Secreted {ECO:0000305PubMed:15880534}. Membrane {ECO:0000305PubMed:15880534}.
Disease Associations
Tissue Specificity Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells. {ECO:0000269PubMed:12019145, ECO:0000269PubMed:12595743, ECO:0000269PubMed:15096563}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016266 O-glycan processing
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005796 Golgi lumen
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96DR8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 118430
UniGene Hs.348419
RefSeq NP_477521
HUGO HGNC:30588
OMIM 610857
CCDS CCDS8885
HPRD 17290
IMGT
EMBL AF414087 AY359062 AY651259 BC111421
GenPept AAI11422 AAL02119 AAQ89421 AAT72303

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca