InnateDB Protein
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IDBP-385196.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NLRP2
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Protein Name
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NLR family, pyrin domain containing 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000402474
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InnateDB Gene
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IDBG-69883 (NLRP2)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
25
[view]
|
Protein-Protein |
25
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0043280
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positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
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GO:0045087
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innate immune response (InnateDB)
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GO:0050718
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positive regulation of interleukin-1 beta secretion
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Cellular Component |
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PDB ID |
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InterPro |
IPR003590
Leucine-rich repeat, ribonuclease inhibitor subtype
IPR007111
NACHT nucleoside triphosphatase
IPR011029
Death-like domain
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00368
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NX02
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PhosphoSite |
PhosphoSite-Q9NX02
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TrEMBL |
K7EPE6
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UniProt Splice Variant |
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Entrez Gene |
55655
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UniGene |
Hs.597119
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RefSeq |
NP_001167554
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HUGO |
HGNC:22948
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OMIM |
609364
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CCDS |
CCDS54318
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HPRD |
14805
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IMGT |
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EMBL |
AB209300
AC011476
AF298547
AF310106
AF464764
AK000517
AK000784
AK025952
AK223253
AK223269
AK302989
BC001039
BC003592
BC039269
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GenPept |
AAG15253
AAG30289
AAH01039
AAH03592
AAH39269
AAL69962
BAA91223
BAA91377
BAB15293
BAD92537
BAD96973
BAD96989
BAG64129
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