Version 5.4
Homo sapiens Protein: HTRA1
Summary
InnateDB Protein IDBP-386431.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTRA1
Protein Name HtrA serine peptidase 1
Synonyms ARMD7; CARASIL; HtrA; L56; ORF480; PRSS11;
Species Homo sapiens
Ensembl Protein ENSP00000412676
InnateDB Gene IDBG-91906 (HTRA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001478 PDZ domain
IPR001940 Peptidase S1C
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PF00595
PF13180
PRINTS PR00834
PIRSF
SMART SM00020
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y7G9
UniProt Splice Variant
Entrez Gene 5654
UniGene Hs.501280
RefSeq
HUGO HGNC:9476
OMIM 602194
CCDS
HPRD 03725
IMGT
EMBL AK092476 AK290089 BX842242
GenPept BAF82778 BAG52557

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca