Version 5.4
Homo sapiens Protein: PRAP1
Summary
InnateDB Protein IDBP-387109.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRAP1
Protein Name proline-rich acidic protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000416126
InnateDB Gene IDBG-93715 (PRAP1)
Protein Structure
UniProt Annotation
Function May play an important role in maintaining normal growth homeostasis in epithelial cells. {ECO:0000269PubMed:14583459}.
Subcellular Localization Secreted {ECO:0000269PubMed:14583459}.
Disease Associations
Tissue Specificity Abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level). {ECO:0000269PubMed:14583459, ECO:0000269PubMed:20736409}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96NZ9
PhosphoSite PhosphoSite-Q96NZ9
TrEMBL A6XND8
UniProt Splice Variant
Entrez Gene 118471
UniGene
RefSeq NP_660203
HUGO HGNC:23304
OMIM 609776
CCDS CCDS7679
HPRD 17898
IMGT
EMBL AF123768 AF421885 AL360181 AY158074 AY358908 BC029447 BC061643 BC071872 BC093853 BC101743 BC143590 BC143591 BC143592 CH471211 DQ884405 GU727628
GenPept AAH29447 AAH61643 AAH71872 AAH93853 AAI01744 AAI43591 AAI43592 AAI43593 AAL16670 AAN87018 AAP97247 AAQ89267 ABI63372 ADU87630 CAH70283 EAW61336

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca