Version 5.4
Homo sapiens Protein: TFPI
Summary
InnateDB Protein IDBP-387938.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TFPI
Protein Name tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Synonyms EPI; LACI; TFI; TFPI1;
Species Homo sapiens
Ensembl Protein ENSP00000394185
InnateDB Gene IDBG-77150 (TFPI)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002223 Proteinase inhibitor I2, Kunitz metazoa
PFAM PF00014
PRINTS PR00759
PIRSF
SMART SM00131
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JT76
UniProt Splice Variant
Entrez Gene 7035
UniGene Hs.619450
RefSeq
HUGO HGNC:11760
OMIM 152310
CCDS
HPRD 01064
IMGT
EMBL AC007319 AC098485
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca