InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STAT1

Summary

InnateDB Protein

IDBP-388063.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STAT1

Protein Name

signal transducer and activator of transcription 1, 91kDa

Synonyms

CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91;

Species

Homo sapiens

Ensembl Protein

ENSP00000388240

InnateDB Gene

IDBG-77617 (STAT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 332 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	332 [view]
Protein-Protein	235 [view]
Protein-DNA	95 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0045087

innate immune response (InnateDB)

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR022752 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal

PFAM

PF12162

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

6772

UniGene

Hs.743244

RefSeq

HUGO

HGNC:11362

OMIM

600555

CCDS

HPRD

02777

IMGT

EMBL

GenPept