Version 5.4
Homo sapiens Protein: PYCRL
Summary
InnateDB Protein IDBP-38810.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYCRL
Protein Name pyrroline-5-carboxylate reductase-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000220966
InnateDB Gene IDBG-38808 (PYCRL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006561 proline biosynthetic process
GO:0055114 oxidation-reduction process
GO:0055129 L-proline biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000304 Pyrroline-5-carboxylate reductase
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
PFAM PF03807
PRINTS
PIRSF PIRSF000193
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q53H96
PhosphoSite PhosphoSite-Q53H96
TrEMBL B5MD87
UniProt Splice Variant
Entrez Gene 65263
UniGene Hs.165186
RefSeq NP_075566
HUGO HGNC:25846
OMIM
CCDS CCDS6407
HPRD 15196
IMGT
EMBL AC067930 AK001500 AK023914 AK222685 AL833857 BC007993
GenPept AAH07993 BAB14721 BAD96405 BAG50927 CAD38716

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca