Version 5.4
Homo sapiens Protein: MOGAT1
Summary
InnateDB Protein IDBP-389122.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOGAT1
Protein Name monoacylglycerol O-acyltransferase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000406674
InnateDB Gene IDBG-82211 (MOGAT1)
Protein Structure
UniProt Annotation
Function Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0004144 diacylglycerol O-acyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006071 glycerol metabolic process
GO:0006651 diacylglycerol biosynthetic process
GO:0019432 triglyceride biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007130 Diacylglycerol acyltransferase
PFAM PF03982
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96PD6
PhosphoSite PhosphoSite-Q96PD6
TrEMBL
UniProt Splice Variant
Entrez Gene 116255
UniGene Hs.344090
RefSeq NP_477513
HUGO HGNC:18210
OMIM 610268
CCDS CCDS46524
HPRD 14729
IMGT
EMBL AC104772 AF384163 BN000154
GenPept AAK84178 AAX81987 CAD89265

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca