Version 5.4
Homo sapiens Protein: RCOR3
Summary
InnateDB Protein IDBP-390001.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCOR3
Protein Name REST corepressor 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000413929
InnateDB Gene IDBG-106489 (RCOR3)
Protein Structure
UniProt Annotation
Function May act as a component of a corepressor complex that represses transcription. {ECO:0000305}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00512, ECO:0000255PROSITE-ProRule:PRU00624}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000949 ELM2 domain
IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like
PFAM PF01448
PF00249
PRINTS
PIRSF
SMART SM00717
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P2K3
PhosphoSite PhosphoSite-Q9P2K3
TrEMBL E9PR63
UniProt Splice Variant
Entrez Gene 55758
UniGene Hs.714992
RefSeq NP_001129695
HUGO HGNC:25594
OMIM
CCDS CCDS44312
HPRD 08338
IMGT
EMBL AB037764 AK001738 AK131312 AK302664 AL590101 AL611964 BC031608
GenPept AAH31608 BAA91872 BAA92581 BAG54764 BAG63899 CAH72432 CAH72433 CAH73871 CAH73872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca