Version 5.4
Homo sapiens Protein: DNAJC14
Summary
InnateDB Protein IDBP-39191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAJC14
Protein Name DnaJ (Hsp40) homolog, subfamily C, member 14
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000317500
InnateDB Gene IDBG-39185 (DNAJC14)
Protein Structure
UniProt Annotation
Function Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney. {ECO:0000269PubMed:12768437}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001623 DnaJ domain
PFAM PF00226
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6Y2X3
PhosphoSite PhosphoSite-Q6Y2X3
TrEMBL F8VYY5
UniProt Splice Variant
Entrez Gene 85406
UniGene Hs.734057
RefSeq
HUGO HGNC:24581
OMIM 606092
CCDS CCDS8894
HPRD 12082
IMGT
EMBL AC023055 AF351784 AK055945 AY188447 BC080655 BC117146 BC117148 CH471054 EF560741
GenPept AAH80655 AAI17147 AAI17149 AAK56241 AAO73451 ABQ59051 BAB71050 EAW96833 EAW96834 EAW96836

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca