InnateDB Protein
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IDBP-39445.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TMEM161A
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Protein Name
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transmembrane protein 161A
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000162044
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InnateDB Gene
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IDBG-39443 (TMEM161A)
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Protein Structure
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Function |
May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis. {ECO:0000269PubMed:16551573}.
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Subcellular Localization |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0032526
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response to retinoic acid
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GO:0034599
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cellular response to oxidative stress
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GO:0034644
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cellular response to UV
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GO:0045739
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positive regulation of DNA repair
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GO:1902230
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negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
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Cellular Component |
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PDB ID |
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InterPro |
IPR019395
Transmembrane protein 161A/B
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PFAM |
PF10268
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NX61
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PhosphoSite |
PhosphoSite-Q9NX61
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TrEMBL |
V9GYP8
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UniProt Splice Variant |
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Entrez Gene |
54929
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UniGene |
Hs.631629
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RefSeq |
NP_060284
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HUGO |
HGNC:26020
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OMIM |
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CCDS |
CCDS12393
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HPRD |
07905
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IMGT |
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EMBL |
AC002126
AK000429
AK096964
AY358088
BC005210
BC016478
CH471106
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GenPept |
AAH05210
AAH16478
AAQ88455
BAA91159
BAG53402
EAW84787
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