Version 5.4
Homo sapiens Protein: TMEM161A
Summary
InnateDB Protein IDBP-39445.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM161A
Protein Name transmembrane protein 161A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000162044
InnateDB Gene IDBG-39443 (TMEM161A)
Protein Structure
UniProt Annotation
Function May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis. {ECO:0000269PubMed:16551573}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0032526 response to retinoic acid
GO:0034599 cellular response to oxidative stress
GO:0034644 cellular response to UV
GO:0045739 positive regulation of DNA repair
GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR019395 Transmembrane protein 161A/B
PFAM PF10268
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NX61
PhosphoSite PhosphoSite-Q9NX61
TrEMBL V9GYP8
UniProt Splice Variant
Entrez Gene 54929
UniGene Hs.631629
RefSeq NP_060284
HUGO HGNC:26020
OMIM
CCDS CCDS12393
HPRD 07905
IMGT
EMBL AC002126 AK000429 AK096964 AY358088 BC005210 BC016478 CH471106
GenPept AAH05210 AAH16478 AAQ88455 BAA91159 BAG53402 EAW84787

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca