InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Inpp5f

Summary

InnateDB Protein

IDBP-400172.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Inpp5f

Protein Name

inositol polyphosphate-5-phosphatase F

Synonyms

5830435P03Rik; AI115354; AW561896; cI-27; mKIAA0966; SAC2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113700

InnateDB Gene

IDBG-210673 (Inpp5f)

Protein Structure

UniProt Annotation

Function

Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5- bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0042578	phosphoric ester hydrolase activity

Biological Process

GO:0014898	cardiac muscle hypertrophy in response to stress
GO:0031161	phosphatidylinositol catabolic process
GO:0048015	phosphatidylinositol-mediated signaling
GO:0051896	regulation of protein kinase B signaling