Version 5.4
Mus musculus Protein: Slc43a1
Summary
InnateDB Protein IDBP-400194.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc43a1
Protein Name solute carrier family 43, member 1
Synonyms 2610016F07Rik; AA986141; Lat3; PB39; Pov1; R00504;
Species Mus musculus
Ensembl Protein ENSMUSP00000112642
InnateDB Gene IDBG-185436 (Slc43a1)
Protein Structure
UniProt Annotation
Function Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine (By similarity). {ECO:0000250UniProtKB:O75387}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015175 neutral amino acid transmembrane transporter activity
GO:0015179 L-amino acid transmembrane transporter activity
Biological Process
GO:0015804 neutral amino acid transport
GO:0015807 L-amino acid transport
GO:0055085 transmembrane transport
GO:1902475 L-alpha-amino acid transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1931352
InterPro IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
PFAM PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BSM7
PhosphoSite PhosphoSite-Q8BSM7
TrEMBL B0R0N4
UniProt Splice Variant
Entrez Gene 72401
UniGene Mm.22716
RefSeq XP_006500291
MGI ID
MGI Symbol Slc43a1
OMIM
CCDS CCDS38163
HPRD
IMGT
EMBL AB103034 AK011417 AK031215 AL928914 BC053747
GenPept AAH53747 BAB27605 BAC27305 BAD10947 CAM23317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca