Version 5.4
Mus musculus Protein: Pex26
Summary
InnateDB Protein IDBP-400593.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pex26
Protein Name peroxisomal biogenesis factor 26
Synonyms 4632428M11Rik; AI853212;
Species Mus musculus
Ensembl Protein ENSMUSP00000113233
InnateDB Gene IDBG-184318 (Pex26)
Protein Structure
UniProt Annotation
Function Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence (By similarity). {ECO:0000250}.
Subcellular Localization Peroxisome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008022 protein C-terminus binding
GO:0032403 protein complex binding
GO:0051117 ATPase binding
Biological Process
GO:0016558 protein import into peroxisome matrix
GO:0045046 protein import into peroxisome membrane
Cellular Component
GO:0005779 integral component of peroxisomal membrane
Protein Structure and Domains
PDB ID MGI:1921293
InterPro IPR010797 Pex26
PFAM PF07163
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGI5
PhosphoSite PhosphoSite-Q8BGI5
TrEMBL D3Z323
UniProt Splice Variant
Entrez Gene 74043
UniGene Mm.487560
RefSeq
MGI ID
MGI Symbol Pex26
OMIM
CCDS
HPRD
IMGT
EMBL AC153584 AK014598 AK040411 AK042663 AK044186 AK087637 AK147925 BC019144 BC058694
GenPept AAH19144 AAH58694 BAB29453 BAC30589 BAC31324 BAC31808 BAC39952 BAE28233

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca