InnateDB Protein
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IDBP-400986.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Slc7a9
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Protein Name
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solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
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Synonyms
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CSNU3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000113181
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InnateDB Gene
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IDBG-174331 (Slc7a9)
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Protein Structure
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Function |
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney proximal tubule.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:12167606}; Multi-pass membrane protein {ECO:0000269PubMed:12167606}.
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Disease Associations |
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Tissue Specificity |
Expressed in the brush border membrane in the kidney (at protein level). {ECO:0000269PubMed:12167606}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0015171
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amino acid transmembrane transporter activity
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GO:0015175
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neutral amino acid transmembrane transporter activity
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GO:0042605
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peptide antigen binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1353656
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InterPro |
IPR002293
Amino acid/polyamine transporter I
IPR004841
Amino acid permease/ SLC12A domain
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PFAM |
PF13520
PF00324
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PRINTS |
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PIRSF |
PIRSF006060
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9QXA6
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3UQE3
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UniProt Splice Variant |
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Entrez Gene |
30962
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UniGene |
Mm.45874
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RefSeq |
NP_001185944
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MGI ID |
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MGI Symbol |
Slc7a9
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OMIM |
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CCDS |
CCDS21150
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HPRD |
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IMGT |
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EMBL |
AF192310
AJ249198
AK142541
BC010746
CH466618
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GenPept |
AAG28396
AAH10746
BAE25099
CAB54042
EDL03015
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