InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ipmk

Summary

InnateDB Protein

IDBP-401119.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ipmk

Protein Name

inositol polyphosphate multikinase

Synonyms

2410017C19Rik; AA408208; Impk;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113083

InnateDB Gene

IDBG-161804 (Ipmk)

Protein Structure

UniProt Annotation

Function

Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000823	inositol-1,4,5-trisphosphate 6-kinase activity
GO:0000824	inositol tetrakisphosphate 3-kinase activity
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity

Biological Process

GO:0001841	neural tube formation
GO:0016310	phosphorylation
GO:0032958	inositol phosphate biosynthetic process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1916968

InterPro

IPR005522 Inositol polyphosphate kinase

PFAM

PF03770

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7TT16

PhosphoSite

PhosphoSite-Q7TT16

TrEMBL

UniProt Splice Variant

Entrez Gene

69718

UniGene

Mm.420969

RefSeq

MGI ID

MGI Symbol

Ipmk

OMIM

CCDS

HPRD

IMGT

EMBL

AK010523 AK036084 AK036978 BC052463

GenPept

AAH52463 BAB27004 BAC29300 BAC29655