Version 5.4
Mus musculus Protein: Stambpl1
Summary
InnateDB Protein IDBP-401174.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stambpl1
Protein Name STAM binding protein like 1
Synonyms 1700095N21Rik; 8230401J17Rik; ALMalpha; AMSH-FP;
Species Mus musculus
Ensembl Protein ENSMUSP00000112938
InnateDB Gene IDBG-159407 (Stambpl1)
Protein Structure
UniProt Annotation
Function Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitously expressed. Isoform 1 is widely expressed while isoform 2 is testis-specific. {ECO:0000269PubMed:12943674}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1923880
InterPro IPR000555 JAB1/MPN/MOV34 metalloenzyme domain
PFAM PF01398
PRINTS
PIRSF
SMART SM00232
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q76N33
PhosphoSite PhosphoSite-Q76N33
TrEMBL Q3UUR8
UniProt Splice Variant
Entrez Gene 76630
UniGene Mm.130952
RefSeq XP_006527514
MGI ID
MGI Symbol Stambpl1
OMIM
CCDS CCDS29756
HPRD
IMGT
EMBL AB010121 AB010122 AB066211 AB066212 AB066213 AC102285 AC165239 AK138126 BC018343
GenPept AAH18343 BAD00166 BAD00167 BAD00168 BAD06408 BAD06409 BAE23556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca